Containing proven, high-quality research articles selected from the popular Proteomics journal, this is a current overview of the latest research into the proteomics analysis of microbial pathogens as well as several review articles.

Peter R. Jungblut is the head of the Department of Protein Analysis, as a core facility of the Max-Planck-Institute for Infection Biology in Berlin, Germany, coordinating all proteomics activities of the institute. By classical proteome analysis, his group generated a proteomic database with about 1500 identified proteins of microorganisms, eucaryotic cells and tissues. He has published more than 130 scientific articles on proteomics.

Michael Hecker is a biologist and became Professor in 1986 at the Ernst-Moritz-Arnd University in Greifswald, where he is also director of the Department for Microbial Physiology and Molecular Biology. He is a member of the Leopoldina, a fellow of the American Academy of Microbiology, as well as member of numerous scientific societies and academic bodies. In 2005 he was elected as the Vice Chair of the International Union of Microbiological Societies. He has published more than 300 scientific articles.

Proteomics of microbial pathogens

Genome and proteome analysis of Chlamydia

Helicobacter pylori vaccine development based on combined subproteome analysis

A comprehensive proteome map of growing Bacillus subtilis cells

A targeted proteomics approach to the rapid identification of bacterial cell mixtures by matrix-assisted laser desorption/ionization mass spectrometry

Proteome analysis of Neisseria meningitidis serogroup A

Protein identification and tracking in two-dimensional electrophoretic gels by minimal protein identifiers

Continued proteomic analysis of Mycobacterium leprae subcellular fractions

CFP10 discriminates between nonacetylated and acetylated ESAT-6 of Mycobacterium tuberculosis by differential interaction

The Helicobacter pylori CagA protein induces tyrosine dephosphorylation of ezrin

Action and Reaction: Chlamydophila pneumoniae proteome alteration in a persistent infection induced by iron deficiency

Assessment of protein spot components applying correspondence analysis for peptide mass fingerprint data

Presentation of differentially regulated proteins within a web-accessible proteome database system of microorganisms

The cell wall subproteome of Listeria monocytogenes

Low virulent strains of Candida albicans: Unravelling the antigens for a future vaccine

Proteomic analysis of the sarcosine-insoluble outer membrane fraction of the bacterial pathogen Bartonella henselae

The influence of agr and B in growth phase dependent regulation of virulence factors in Staphylococcus aureus

Comparative proteome analysis of cellular proteins extracted from highly virulent Francisella tularensis ssp. tularensis and less virulent F. tularensis ssp. holarctica and F. tularensis ssp. mediaasiatica

Proteome comparison of Vibrio cholerae cultured in aerobic and anaerobic conditions

Highly phosphorylated bacterial proteins

Induction of Mycobacterium avium proteins upon infection of human macrophages

Proteomics-based identification of novel Candida albicans antigens for diagnosis of systemic candidiasis in patients with underlying hematological malignancies